Luis De Jesus Los Angeles is a contemporary art gallery representing emerging and mid-career artists who are engaged in regional and global art discourse with a particular focus on intersectional diversity. These artists use conceptual and formal strategies as a critical lens to address a myriad of concerns including the social constructs of gender, racial, and subjective identity, the power of aesthetic frameworks to shape political and economic reality, and the historical role of the artist within society.

Luis De Jesus Los Angeles opened in Santa Monica's Bergamot Station in 2010 and relocated in 2011 to the Culver City Arts District, where the gallery operated for ten years. In 2021, the gallery opened an expansive space in the downtown Los Angeles Arts District.